Biomarkers
Companion Diagnostics | Disease Progression | Therapeutic Success
Biomarkers based on high-resolution nucleic acid analyses in tissue, blood and urine.
We are profiling mRNA, smallRNA (microRNA), non-coding RNA, DNA, methylation of the DNA (epigenetics) and examine specific characteristics of them for high-resolution biomarker identification. Based on the findings, qPCR- or other single- or multigene assays are developed for cost-efficient biomarker analyses.
We develop biomarkers based on:
DNA (Tissue or cfDNA / Liquid Biopsies)
- Single Nucleotide Polymorphisms (SNPs) / mutations
- Copy Number Variations (CNVs)
- DNA-methylation patterns (epigenetics)
mRNA
- differential expression
- biological pathways
- gene fusions
- truncated RNA and Alternative Polyadenylation (APA)
smallRNA (tissue or Exo-RNA = liquid biopsies)
- differential expression
- mutations