From Sequence Reads to Achievements
State of the Art Bioinformatics for all your NGS Data
Unleash the Full Potential of Next-Generation Sequencing: Simply upload your NGS Illumina raw-data or fastqc data to our webserver, start the required analyses and receive your results a few minutes to hours later.
We offer:
- Data Preprocessing: clean, filter, and quality-check of the data
- Alignment and Variant Calling: Align the sequenced fragments to the reference genome of choice and identify genetic variations and
- Data Interpretation: Complex algorithms and analytical tools transform your raw data into insights
Our powerful graphics-card based analyses pipelines are available for
- Whole Genome Sequencing (WGS)
- Whole Exome Sequencing (WES)
- RNA-Seq
- MACE-Seq (3′ mRNA-Seq)
- smallRNA-Seq
- Microbiome
- Amplicons & Aptamers
Please visit https://tools.genxpro.net or send us an email at info@genxpro.net for further information.
We are chosen by leading academic and commercial research units worldwide as partners for data analysis and have successfully contributed to numerous publications. Besides, we have also designed our own web-based and highly accessed analysis tools, available for everyone (omiRas and APADB).
Our web suite navigates you through your own data and connects and compares them with the known data from databases worldwide.
Curious ? Please access examplary data on our server at https://tools.genxpro.net
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Password: testtest
Data can be delivered in all usual formats, the final results typically in a table which can readily be analyzed using Excel. Data is provided conveniently via secured FTP or by shipping of a hard-disk.
Fast access to the actual state of knowledge by comprehensive annotation to all publicly available databases
By constantly evaluating and collecting the available information from the many different open source databases and publications, we have generated a huge knowledge base of functional annotations, which we are constantly feeding with further information. The database is for research use only. We provide fast access to the available clinical information from
- Variants, CNVs and Fusions
- Small RNAs
- Gene expression data
- Epigenetic data
Machine Learning: Finding what matters in the data jungle!
With the help of advanced machine learning techniques and deep learning we pinpoint causative players from the myriad of genomic datasets available online and generated in-house.
Our know-how is fundamental for precision medicine and therapeutic decisions, to determine and classify important subsets of genes, mutations or epigenetic changes. We apply our machine-learning expertise also to any other area with similar data structure, such as for metagenomics or for plant breeding.
Genome and Exome
- SNPs
- Indels
- Rearrangements
- Copy Number Variations (CNVs)
- Genotyping
- Generation of linkage maps
- QTL analyses
- Genomic Selection
Microbiome
- Annotation / identification of organisms
- Annotation to protein databases
- Quantification of organisms
- Graphical representation of the data
PCR Bias Elimination
As inventors of the TrueQuant method, we can identify and eliminate PCR introduced copies and bias, for much better quantification and more reliable mutation calling.
Druggability Analyses / Theranostics
Our unique analyses tool identifies differential regulated transcripts, translates them into biological pathways and identifies in the vast repertoire of existing drugs the ones with the strongest likelihood to intervene in these pathways.
New therapeutic options become visible in a few mouse clicks
All the information onto which the decision is based are clearly documented and links to the databases, research papers, drugs and genes are provided for fast and comprehensive information.
Plant research and breeding, model and non-model organisms
We are chosen by numerous breeding companies and institutes world-wide for NGS bioinformatics analyses in the field of plant-breeding. Our unique annotation pipeline includes all available protein information as well as data from related species for the most accurate identification of genes of a trait of interest from genomics and transcriptomics data. We are specialists for do-novo assemblys, GBS, QTL and eQTL analyses of model and non-model plants and organisms.
Primer design for microbes
We apply algorithms from NGS data analyses pipelines to quickly identify uniqe genetic information, for example from a species or variant within a microbiome, that we use to design highly specific primer pairs for PCR and qPCR assays.
Any special Requests?
Collaboration: Engage with our experts, tapping into their knowledge to drive your research forward.
Together with our customers we develop tailored analysis modules for your specific needs. Our pipelines are also open for data that was generated independently from us. Please do not hesitate to contact us with any special requests or for the interpretation of your NGS data.
