Smart NGS Solutions and Bioinformatics for Research and Health

From minute amounts of material to high-resolution data:  full service or kits for all your samples

Plan your next NGS project with us here

News

We revised our data-analyses and quotation website for better usability and new analyses options! https://tools.genxpro.net/   New Collaboration We are proud to be among the 20 companies that received a grant from “INNOWWIDE” (https://innowwide.eu/) to examine the market in Algeria for our innovative RNA-based cancer therapy decision support system “ClinXPro” in collaboration with the Centre de Recherche en Sciences Pharmaceutiques (CRSP; https://crsp.dz/) – a special thanks for the great support to Christian Garbe (https://lnkd.in/eV4Y6TZE) and his team of the Frankfurt Innovation Center (FIZ) for making this possible. We are looking forward for this great opportunity!

Recent Papers Bulked segregant transcriptome analysis in pea identifies key expression markers for resistance to Peyronellaea pinodes. Fondevilla S, Krezdorn N, Rubiales D, Rotter B, Winter P. Sci Rep. 2022 Oct 28;12(1):18159. doi: 10.1038/s41598-022-22621-2. PMID: 36307494   Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host.   Sonnleitner ST, Prelog M, Sonnleitner S, Hinterbichler E, Halbfurter H, Kopecky DBC, Almanzar G, Koblmüller S, Sturmbauer C, Feist L, Horres R, Posch W, Walder G. Nat Commun. 2022 May 10;13(1):2560. doi: 10.1038/s41467-022-30163-4. PMID: 35538074   The methylome in females with adolescent Conduct Disorder: Neural pathomechanisms and environmental risk factors.   Chiocchetti AG, Yousaf A, Waltes R, Bernhard A, Martinelli A, Ackermann K, Haslinger D, Rotter B, Krezdorn N, Konrad K, Kohls G, Vetro A, Hervas A, Fernández-Rivas A, Freitag CM. PLoS One. 2022 Jan 28;17(1):e0261691. doi: 10.1371/journal.pone.0261691. eCollection 2022. PMID: 35089926 Free PMC article. Clinical Trial.   Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart.   Bräuninger H, Stoffers B, Fitzek ADE, Meißner K, Aleshcheva G, Schweizer M, Weimann J, Rotter B, Warnke S, Edler C, Braun F, Roedl K, Scherschel K, Escher F, Kluge S, Huber TB, Ondruschka B, Schultheiss HP, Kirchhof P, Blankenberg S, Püschel K, Westermann D, Lindner D. Cardiovasc Res. 2022 Jan 29;118(2):542-555. doi: 10.1093/cvr/cvab322. PMID: 34647998      Autopolyploidization affects transcript patterns and gene targeting frequencies in Physcomitrella.   Rempfer C, Wiedemann G, Schween G, Kerres KL, Lucht JM, Horres R, Decker EL, Reski R. Plant Cell Rep. 2022 Jan;41(1):153-173. doi: 10.1007/s00299-021-02794-2. Epub 2021 Oct 12. PMID: 34636965

Experts for sample preparation, sequencing and bioinformatics:

Transcriptomics, Genomics, Epigenomics, Metagenomics

By combining intelligent sample preparation with latest next generation sequencing methods, we analyse transcriptomes, genomes and epigenomes at highest resolution.

Our service comprises project planning, consulting, sample preparation, sequencing and bioinformatics.

In 2008 we invented “TrueQuant” – applying unique molecule identifiers for PCR bias reduction of NGS data.

Thanks to many years of experience with deep sequencing, we have accumulated vast knowledge in low-bias sample preparation of all kinds of different biological samples and provide appropriate data analyses solutions for all areas of life sciences.

Our team of bioinformaticians apply the most advanced methods and designs individual solutions to handle the data on our powerful CPU clusters in order to provide the optimal analysis pipelines for your data.

Data is delivered in a ready-to-use format and includes quality information, quantification, annotation, mapping, Gene Ontology analysis, GSEA and ready to use plots and other graphics.

Our portfolio comprises

Precision Medicine, Theranostics, Liquid Biopsy, ctDNA, cfDNA,  Illumina,  RNAseq, deep Sequencing, massively parallel sequencing, 3’Seq, exosomes, small RNA, miRNA, micro RNA, SuperSAGE, MACE, Massive Analysis of cDNA Ends, PARE, Transcriptomics, De novo Sequencing, Assembly, SNPs, Copy Number Variations (CNVs) , RC-Seq (a variant of RADseq), Genotyping by Sequencing, GBS,  Normalisation of cDNA and DNA, CpG Islands, Methylation, MethylSeq, Exome Sequencing, Target enrichment, qPCR,  Bioinformatics, SMART Breeding, Tag-Seq, TagSeq, TrueQuant, UMI, Molecular Barcodes, Target sequencing of Poly-A tags, PATs, ATAC-Seq, Microbiome, Metagenome; Amplicon-Seq, small RNA sequencing from palsma, serum (blood).

Disclaimer

Our services and producs are for research use only.

For testimonials please click here.

 

From tissue to results- full service or kits for all your samples