SARS-CoV-2 VoC qPCR Assay for B.1.617 

Simultaneous SARS-CoV-2 & VoC-PCR for Variant of Concern B.1.617 (“Indian Variant” including the “Delta Variant”)

What is the B.1.617 Variant ?

The B.1.617 variant is known today to be one of the most contageous variants of SARS-CoV-2 and has led to increasing incidents especially in the UK but it was found by now in more than 67 countries including Germany. The variant is also thought to cause a more severe disease and in younger patients. The variant has several mutations in the spike protein that are different from the other variants of concern (VoCs) and is also referred to as “double mutant”. The WHO has recently renamed the most widely spread sub-variant “B.1.617.2” as  “Delta Variant”,

Besides the N-gene, our assay specifically detects the P681R or the N452R mutation, both of which are specific for the VoC B.1.617 including the Delta variant.

Perform the assay on common qPCR instruments with detection channels of FAM and JOE.

The assay can be ideally be combined with our N501Y & delta69/70 and the E484K assay for VoC determination.

Only one qPCR reaction is needed for fastest results.

The assay is for research use only at the moment. CE-IVD is in progress.

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